佐藤講師の研究業績についてはresearchmapを参照してくさい。
2025
1.Fumito Naganuma, Mudasir Khanday, Sathyajit Sai Bandaru, Whidul Hasan, Kyosuke Hirano,Takeo Yoshikawa,Ramalingam Vetrivelan, Regulation of wakefulness by neurotensin neurons in the lateral hypothalamus, Exp Neurol 383, 115035, 2025 https://doi.org/10.1016/j.expneurol.2024.115035
2024
1.Fumito Naganuma, Birkan Girgin, Anne Bernadette S Agu, Kyosuke Hirano, Tadaho Nakamura, Kazuhiko Yanai, Ramalingam Vetrivelan, Takatoshi Mochizuki, Masashi Yanagisawa, Takeo Yoshikawa, Pharmacological inhibition of histamine N-methyltransferase extends wakefulness and suppresses cataplexy in a mouse model of narcolepsy, Sleep zsae244, 2024 https://doi.org/10.1093/sleep/zsae244
2023
1. Fumito Naganuma, Daiki Murata, Marie Inoue, Yuri Maehori, Ryuichi Harada, Shozo Furumoto, Yukitsuka Kudo, Tadaho Nakamura, Nobuyuki Okamura,A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer's Disease Mouse Model. Mol Imaging Biol 25: 1115-1124, 2023, DOI: 10.1007/s11307-023-01843-4
2. Kensuke Sakaji, Sara Ebrahimiazar, Yasuhiro Harigae, Kenichi Ishibashi, Takeya Sato, Takeo Yoshikawa, Gen-ichi Atsumi, Ching-Hwa Sung, Masaki Saito,MAST4 promotes primary ciliary resorption through phosphorylation of Tctex-1, Life Science Alliance 6(11) e202301947-e202301947 2023, DOI: 10.26508/lsa.202301947
3. Nami Tateyama, Teizo Asano, Tomohiro Tanaka, Yu Isoda, Yuki Okada, Hiyori Kobayashi, Guanjie Li, Ren Nanamiya, Takeo Yoshikawa, Mika K Kaneko, Hiroyuki Suzuki, Yukinari Kato, Epitope Mapping of Anti-Mouse CCR3 Monoclonal Antibodies (C3Mab-6 and C3Mab-7). Monoclon Antib Immunodiagn Immunother 42(2) 68-72 2023 DOI: 10.1089/mab.2022.0034
4. Yu Isoda, Tomohiro Tanaka, Hiroyuki Suzuki, Teizo Asano, Kaishi Kitamura, Yuma Kudo, Ryo Ejima, Kazuki Ozawa, Takeo Yoshikawa, Mika K Kaneko, Yukinari Kato, Epitope Mapping of the Novel Anti-Human CCR9 Monoclonal Antibody (C9Mab-11) by 2 × Alanine Scanning. Monoclon Antib Immunodiagn Immunother 42(2) 73-76 2023 DOI: 10.1089/mab.2022.0035
5. Guanjie Li, Hiroyuki Suzuki, Tomohiro Tanaka, Teizo Asano, Takeo Yoshikawa, Mika K Kaneko, Yukinari Kato
, Epitope Mapping of an Anti-EpCAM Monoclonal Antibody (EpMab-37) Using the Alanine Scanning Method.
Monoclon Antib Immunodiagn Immunother 42(1) 41-47 2023 DOI: 10.3892/ijmm.2023.5221
2022
1. Rina Otsuka, Fumito Naganuma, Tadaho Nakamura, Hideki Miwa, Rumi Nakayama-Naono, Takuro Matsuzawa, Yurika Komatsu, Yuki Sato, Yuna Takahashi, Haruna Tatsuoka-Kitano, Kazuhiko Yanai, Takeo Yoshikawa*, Contribution of astrocytic histamine N-methyltransferase to histamine clearance and brain function in mice. Neuropharmacology 212: 109065, 2022, DOI: 10.1016/j.neuropharm.2022.109065
2. Tomomitsu Iida, Kazuhiko Yanai, Takeo Yoshikawa*, Histamine and Microglia, Curr Top Behav Neurosci 59: 241-259, 2022, DOI:10.1007/7854_2022_322
3. Tadaho Nakamura, Fumito Naganuma, Uta Kudomi, Sueji Roh, Kazuhiko Yanai, Takeo Yoshikawa*, Oral histidine intake improves working memory through the activation of histaminergic nervous system in mice. Biochem Biophys Res Commun609: 141-148, 2022, DOI: 10.1016/j.bbrc.2022.04.016
4. Hiyori Kobayashi, Teizo Asano, Hiroyuki Suzuki, Tomohiro Tanaka, Takeo Yoshikawa, Mika K. Kaneko, Yukinari Kato, Establishment of a Sensitive Monoclonal Antibody Against Mouse CCR9 (C9Mab-24) for Flow Cytometry, Monoclon Antib Immunodiagn Immunother, 42: 15-21, 2022, DOI: 10.1089/mab.2022.0032
5. Nami Tateyama, Teizo Asano, Hiroyuki Suzuki, Guanjie Li, Takeo Yoshikawa, Tomohiro Tanaka, Mika K. Kaneko, Yukinari Kato, Epitope Mapping of Anti-Mouse CCR3 Monoclonal Antibodies Using Flow Cytometry, Antibodies 11: 75, 2022, DOI: 10.3390/antib11040075
6. Teizo Asano, Tomohiro Tanaka, Hiroyuki Suzuki, Guanjie Li, Tomokazu Ohishi, Manabu Kawada, Takeo Yoshikawa, Mika K. Kaneko, Yukinari Kato, A Defucosylated Anti-EpCAM Monoclonal Antibody (EpMab-37-mG2a-f) Exerts Antitumor Activity in Xenograft Model, Antibodies 4: 74, 2022, DOI: 10.3390/antib11040074
7. Ren Nanamiya, Tomokazu Ohishi, Hiroyuki Suzuki, Takuya Mizuno, Takeo Yoshikawa, Teizo Asano, Tomohiro Tanaka, Mika K. Kaneko, Yukinari Kato, Defucosylated Mouse-Dog Chimeric Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody (H77Bf) Exerts Antitumor Activities in Mouse Xenograft Models of Canine Osteosarcoma, Monoclon Antib Immunodiagn Immunother, 42: 27-33, 2022, DOI: 10.1089/mab.2022.0022
8. Nami Tateyama, Hiroyuki Suzuki, Tomokazu Ohishi, Teizo Asano, Tomohiro Tanaka, Takuya Mizuno, Takeo Yoshikawa, Manabu Kawada, Mika K. Kaneko, Yukinari Kato, Antitumor Activity of an Anti-EGFR/HER2 Bispecific Antibody in a Mouse Xenograft Model of Canine Osteosarcoma. Pharmaceutics 14: 2494, 2022, DOI: 10.3390/pharmaceutics14112494
9. Teizo Asano, Tomohiro Tanaka, Hiroyuki Suzuki, Guanjie Li, Ren Nanamiya, Nami Tateyama, Yu Isoda, Yuki Okada, Hiyori Kobayashi, Takeo Yoshikawa, Mika K. Kaneko, Yukinari Kato, Development of a Novel Anti-Mouse CCR6 Monoclonal Antibody (C6Mab-13) by N-Terminal Peptide Immunization, Monoclon Antib Immunodiagn Immunother, 41: 343-349, 2022 DOI: 10.1089/mab.2022.0021
10. Hiroyuki Suzuki, Teizo Asano, Tomokazu Ohishi, Takeo Yoshikawa, Hiroyoshi Suzuki, Takuya Mizuno, Tomohiro Tanaka, Manabu Kawada, Mika K. Kaneko, Yukinari Kato, Antitumor Activities in Mouse Xenograft Models of Canine Fibroblastic Tumor by Defucosylated Mouse-Dog Chimeric Anti-HER2 Monoclonal Antibody (H77Bf), Monoclon Antib Immunodiagn Immunother, 42: 34-40, 2022, DOI: 10.1089/mab.2022.0023
11. Tomohiro Tanaka, Hiroyuki Suzuki, Yu Isoda, Teizo Asano, Takuro Nakamura, Miyuki Yanaka, Saori Handa, Nozomi Takahashi, Saori Okuno, Takeo Yoshikawa, Guanjie Li, Ren Nanamiya, Nohara Goto, Nami Tatemiya, Yuki Okada, Hiyori Kobayashi, Mika K. Kaneko, Yukinari Kato, Development of a Sensitive Anti-Human CCR9 Monoclonal Antibody (C9Mab-11) by N-Terminal Peptide Immunization, Monoclon Antib Immunodiagn Immunother 41: 303-310, 2022, DOI: 10.1089/mab.2022.0027
12. Yu Isoda, Tomohiro Tanaka, Hiroyuki Suzuki, Teizo Asano, Takeo Yoshikawa, Kaishi Kitamura, Yuma Kudo, Ryo Ejima, Kazuki Ozawa, Mika K. Kaneko, Yukinari Kato, Epitope Mapping Using the Cell-Based 2 × Alanine Substitution Method About the Anti-mouse CXCR6 Monoclonal Antibody, Cx6Mab-1, Monoclon Antib Immunodiagn Immunother 42: 22-26, 2022, DOI: 10.1089/mab.2022.0029
13. Tomohiro Tanaka, Hiroyuki Suzuki, Teizo Asano, Guanjie Li, Ren Nanamiya, Nami Tateyama, Yu Isoda, Yuki Okada, Hiyori Kobayashi, Takeo Yoshikawa, Mika K. Kaneko, Yukinari Kato, Epitope Mapping of an Anti-Mouse CCR2 Monoclonal Antibody (C2Mab-6) Using Enzyme-Linked Immunosorbent Assay, Monoclon Antib Immunodiagn Immunother, 41: 339-342, 2022, DOI: 10.1089/mab.2022.0020
14. Masaki Saito, Hiroyuki Suzuki, Teizo Asano, Tomohiro Tanaka, Takeo Yoshikawa, Mika K. Kaneko, Yukinari Kato, KLMab-1: An Anti-human KLRG1 Monoclonal Antibody for Immunocytochemistry, Monoclon Antib Immunodiagn Immunother, 41: 279-284, 2022, DOI: 10.1089/mab.2022.0016
15. Yu Isoda, Tomohiro Tanaka, Hiroyuki Suzuki, Teizo Asano, Takuro Nakamura, Miyuki Yanaka, Saori Handa, Yu Komatsu, Saori Okuno, Nozomi Takahashi, Yuki Okada, Hiyori Kobayashi, Guanjie Li, Ren Nanamiya, Nohara Goto, Nami Tatemiya, Takeo Yoshikawa, Mika K. Kaneko, Yukinari Kato, Epitope Mapping of an Anti-Mouse CXCR6 Monoclonal Antibody (Cx6Mab-1) Using the 2 × Alanine Scanning Method, Monoclon Antib Immunodiagn Immunother, 41: 275-278, 2022, DOI: 10.1089/mab.2022.0019
16. Tomohiro Tanaka, Hiroyuki Suzuki, Guanjie Li, Ren Nanamiya, Yu Isoda, Yuki Okada, Hiyori Kobayashi, Takeo Yoshikawa, Mika K. Kaneko, Yukinari Kato, Epitope Mapping of the Anti-Human CC Chemokine Receptor Type-2 Monoclonal Antibody (K036C2), Monoclon Antib Immunodiagn Immunother, 41: 285-289, 2022, DOI: 10.1089/mab.2022.0018
17. Hiroyuki Suzuki, Tomokazu Ohishi, Teizo Asano, Tomohiro Tanaka, Masaki Saito, Takuya Mizuno, Takeo Yoshikawa, Manabu Kawada, Mika Kaneko, Yukinari Kato, Defucosylated mouse‑dog chimeric anti‑HER2 monoclonal antibody exerts antitumor activities in mouse xenograft models of canine tumors, Oncol Rep 48: 154, 2022, DOI: 10.3892/or.2022.8366
2021
1. Matsuzawa T, Morita M, Shimane A, Otsuka R, Mei Y, Irie F, Yamaguchi Y, Yanai K, Yoshikawa T* Heparan sulfate promotes differentiation of white adipocytes to maintain insulin sensitivity and glucose homeostasis. J Biol Chem 297: 101006, 2021
2. Naganuma F, Nakamura T, Kuroyanagi H, Tanaka M, Yoshikawa T, Yanai K, Okamura N. Chemogenetic modulation of histaminergic neurons in the tuberomamillary nucleus alters territorial aggression and wakefulness. Sci Rep 11: 17935, 2021
3. Naganuma F, Yoshikawa T*. Organic Cation Transporters in Brain Histamine Clearance: Physiological and Psychiatric Implications. Handb Exp Pharmacol 266:169-185, 2021
4. Yoshikawa T*, Nakamura T, Yanai K. Histaminergic neurons in the tuberomammillary nucleus as a control centre for wakefulness. Br J Pharmacol 178: 750-769, 2021
5. Yanai K, Yoshikawa T, Church MK, Efficacy and Safety of Non-brain Penetrating H 1-Antihistamines for the Treatment of Allergic Diseases. Curr Top Behav Neurosci 2022, 59: 193-214
2020
1. Yamada Y, Yoshikawa T*, Naganuma F, Kikkawa T, Osumi N, Yanai K. Chronic brain histamine depletion in adult mice induced depression-like behaviours and impaired sleep-wake cycle. Neuropharmacology 175: 108179, 2020 (*: corresponding author)
2. Yokoyama M, Matsuzawa T, Yoshikawa T*, Nunomiya A, Yamaguchi Y, Yanai K. Heparan sulfate controls skeletal muscle differentiation and motor functions. Biochim Biophys Acta Gen Subj 1864: 129707, 2020
2019
1. Kárpáti A, Yoshikawa T*, Naganuma F, Matsuzawa T, Kitano H, Yamada Y, Yokoyama M, Futatsugi A, Mikoshiba K, Yanai K. Histamine H1 receptor on astrocytes and neurons controls distinct aspects of mouse behaviour. Sci Rep 9(1):16451, 2019 (*: corresponding author)
2．Nakamura T, Hiraoka K, Harada R, Matsuzawa T, Ishikawa Y, Funaki Y, Yoshikawa T, Tashiro M, Yanai K, Okamura N. Brain histamine H1 receptor occupancy after oral administration of desloratadine and loratadine. Pharmacol Res Perspect 7(4):e00499, 2019
3. Naganuma F, Kroeger D, Bandaru S, Absi G, Madara J, Vetrivelan R, Lateral hypothalamic neurotensin neurons promote arousal and hyperthermia. PLos Biol 17(3): e3000172, 2019, DOI: 10.1371/journal.pbio.3000172
4. Naganuma F, Bandaru S, Absi G, Chee M, Vetrivelan R, melanin-concentrating hormone neurons promote rapid eye movement sleep independent of glutamate release, Brain Struct Funct 224: 99-110, 2019 DOI: 10.1007/s00429-018-1766-2
5. Naganuma F, Bandaru S, Absi G, Mahoney C, Scammell T, Vetrivelan R, Melanin-concentrating hormone neurons contribute to dysregulation of rapid eye movement sleep in narcolepsy. Neurobiol Dis 120: 12-20, 2018, DOI: 10.1016/j.nbd.2018.08.012
2018以前
1. Karpati A, Yoshikawa T*, Nakamura T, Iida T, Matsuzawa T, Kitano H, Harada R, Yanai K. Histamine elicits glutamate release from cultured astrocytes. J Pharmacol Sci 137: 122-128, 2018 (*: corresponding author)
2. Matsuzawa T, Yoshikawa T*, Iida T, Kárpáti A, Kitano H, Harada R, Nakamura T, Sugawara A, Yamaguchi Y, Yanai K. Heparan sulfate in pancreatic β-cells contributes to normal glucose homeostasis by regulating insulin secretion. Biochem Biophys Res Commun 499: 688-695, 2018 (*: corresponding author)
3. Aoki S, Saito-Hakoda A, Yoshikawa T, Shimizu K, Kisu K, Takagi K, Mizumoto S, Yamada S, Kuppervelt T, Yokoyama A, Matusaka T, Sato H, Ito S, Sugawara A. The reduction of heparan sulphate in the glomerular basement membrane does not augment urinary albumin excretion. Nephrol Dial Transplant 33:26-33, 2018
4. Eguchi K, Shindo T, Ito K, Ogata T, Kurosawa R, Kagaya Y, Monma Y, Ichijo S, Kasukabe S, Miyata S, Yoshikawa T, Yanai K, Taki H, Kanai H, Osumi N, Shimokawa H. Whole-brain low-intensity pulsed ultrasound therapy markedly improves cognitive dysfunctions in mouse models of dementia - Crucial roles of endothelial nitric oxide synthase. Brain Stimul 11: 959-973, 2018
5. Yanai A, Harada R, Iwata R, Yoshikawa T, Ishikawa Y, Furumoto S, Ishida T, Yanai K. Site-Specific Labeling of F-18 Proteins Using a Supplemented Cell-Free Protein Synthesis System and O-2-[18F]Fluoroethyl-L-Tyrosine: [18F]FET-HER2 Affibody Molecule. Mol Imaging Biol 21: 529-537, 2018
6. Naganuma F, Nakamura T, Yoshikawa T*, Iida T, Miura Y, Kárpáti A, Matsuzawa T, Yanai A, Mogi A, Mochizuki T, Okamura N, Yanai K. Histamine N-methyltransferase regulates aggression and the sleep-wake cycle. Sci Rep 7: 15899, 2017 (*: corresponding author)
7. Inoue SI, Takahara S, Yoshikawa T, Niihori T, Yanai K, Matsubara Y, Aoki Y. Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice. Hum Mol Genet. 26: 4715-4727, 2017
8. Yanai K, Yoshikawa T*, Yanai A, Nakamura T, Iida T, Leurs R, Tashiro M. The clinical pharmacology of non-sedating antihistamines. Pharmacol Ther. 178: 148-156, 2017 (*: corresponding author)
9. Kishimoto Y, Asakawa S, Sato T, Takano T, Nakajyo T, Mizuno N, Segawa R, Yoshikawa T, Hiratsuka M, Yanai K, Ohtsu H, Hirasawa N. Induced histamine regulates Ni elution from an implanted Ni wire in mice by downregulating neutrophil migration. Exp Dermatol. 26: 868-874, 2017
10. Yoshikawa T* and Yanai K, Histamine clearance through polyspecific transporters in the brain. Handbook Exp Pharmacol 241: 173-187, 2017 (*: corresponding author)
11. Miura Y, Yoshikawa T*, Naganuma F, Nakamura T, Iida T, Kárpáti A, Matsuzawa T, Mogi A, Harada R, Yanai K. Characterization of murine polyspecific monoamine transporters. FEBS Open Bio 7: 237-248, 2017 (*: corresponding author)
12. Iida T, Yoshikawa T*, Kárpáti A, Matsuzawa T, Kitano H, Mogi A, Harada R, Naganuma F, Nakamura T, Yanai K. JNJ10181457, a histamine H3 receptor inverse agonist, regulates in vivo microglial functions and improves depression-like behaviours in mice. Biochem Biophys Res Commun. 488: 534-540, 2017 (*: corresponding author)
13. Harada R, Furumoto S, Yoshikawa T, Ishikawa Y, Shibuya K, Okamura N, Ishiwata K, Iwata R, Yanai K. Synthesis and Characterization of 18F-Interleukin-8 Using a Cell-Free Translation System and 4-18F-Fluoro-l-Proline J Nucl Med 57: 634-639, 2016
14. Saito-Hakoda A, Uruno A, Yokoyama A, Shimizu K, Parvin R, Kudo M, Saito-Ito T, Sato I, Kogure N, Suzuki D, Shimada H, Yoshikawa T, Fujiwara I, Kagechika H, Iwasaki Y, Kure S, Ito S, Sugawara A. Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression. PLoS One 10: e0141960, 2015
15. Sato H, Ito C, Hiraoka K, Tashiro M, Shibuya K, Funaki Y, Yoshikawa T, Iwata R, Matsuoka H, Yanai K. Histamine H1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers. Psychopharmacology (Berl) 232: 3497-3505, 2015
16. Iida T, Yoshikawa T*, Matsuzawa T, Naganuma F, Nakamura T, Miura Y, Mohsen AS, Harada R, Iwata R, Yanai K. Histamine H3 receptor in primary mouse microglia inhibits chemotaxis, phagocytosis, and cytokine secretion. Glia 63: 1213-1225, 2015 (*: corresponding author)
17. Harada R, Okamura N, Furumoto S, Furukawa K, Ishiki A, Tomita N, Hiraoka K, Watanuki S, Shidahara M, Miyake M, Ishikawa Y, Matsuda R, Inami A, Yoshikawa T, Tago T, Funaki Y, Iwata R, Tashiro M, Yanai K, Arai H, Kudo Y. [(18)F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer's disease, Eur J Nucl Med Mol Imaging 42: 1052-61, 2015
18. Murakami M, Yoshikawa T, Nakamura T, Ohba T, Matsuzaki Y, Sawamura D, Kuwasako K, Yanagisawa T, Ono K, Nakaji S, Yanai K. Involvement of the histamine H1 receptor in the regulation of sympathetic nerve activity. Biochem Biophys Res Commun 458: 584-589, 2015
19. Suzuki H, Sumiyoshi A, Matsumoto Y, Duffy BA, Yoshikawa T, Lythgoe MF, Yanai K, Taki Y, Kawashima R, Shimokawa H. Structural abnormality of the hippocampus associated with depressive symptoms in heart failure rats. Neuroimage 105: 84-92, 2015
20. Kasajima A, Fujishima F, Morikawa T, Kawasaki S, Konosu-Fukaya S, Shibahara Y, Nakamura T, Yoshikawa T, Iijima K, Koike T, Watanabe M, Shibata C, Sasano H. G-cell hyperplasia of the stomach induces ECL-cell proliferation in the pyloric glands in a paracrinal manner. Pathol Int 65: 259-263, 2015
21. Yoshikawa T, Nakamura T, Shibakusa T, Sugita M, Naganuma F, Iida T, Miura Y, Mohsen A, Harada R, Yanai K. Insufficient intake of L-histidine reduces brain histamine and causes anxiety-like behaviors in male mice. J Nutr 144: 1637-1641, 2014
22. Nakamura T, Yoshikawa T*, Naganuma F, Mohsen A, Iida T, Miura Y, Sugawara A, Yanai K. Role of histamine H3 receptor in glucagon-secreting αTC1.6 cells. FEBS Open Bio 5: 36-41, 2014 (*: corresponding author)
23. Naganuma F, Yoshikawa T*, Nakamura T, Iida T, Harada R, Mohsen A, Yamato M, Yanai K, Predominant role of plasma membrane monoamine transporters in monoamine transport in 1321N1, a human astrocytoma-derived cell line. J Neurochem 129: 591-601, 2014 (*: corresponding author)
24. Mohsen A, Yoshikawa T*, Miura Y, Nakamura T, Naganuma F, Shibuya K, Iida T, Harada R, Okamura N, Watanabe T, Yanai K, Mechanism of the Histamine H3 Receptor-mediated Increase in Exploratory Locomotor Activity and Anxiety-like Behaviours in Mice. Neuropharmacology 81: 188-194, 2014 (*: corresponding author)
25. Nakamura T**, Yoshikawa T*, **, Noguchi N, Sugawara A, Kasajima A, Sasano H, Yanai K, The expression and function of histamine H3 receptor in pancreatic β-cells, Br J Pharamacol 171: 171-185, 2014 (*: corresponding author, **: co-first author)
26. Matsuda K, Uruno A, Kogure N, Sugawara K, Shimada H, Nezu M, Saito-Ito T, Iki Y, Kudo M, Shimizu K, Sato I, Yoshikawa T, Satoh F, Ito R, Yokoyama A, Rainey WE, Saito-Hakoda A, Ito S, Sugawara A. Angiotensin II receptor blockers differentially affect CYP11B2 expression in human adrenal H295R cells. Mol Cell Endocrinol 383: 60-68, 2014
27. Guo Y, Niu K, Okazaki T, Wu H, Yoshikawa T, Ohrui T, Furukawa K, Ichinose M, Yanai K, Arai H, Huang G, Nagatomi R. Coffee treatment prevents the progression of sarcopenia in aged mice in vivo and in vitro. Exp Gerontol 50: 1-8, 2014
28. Harada R, Okamura N, Furumoto S, Yoshikawa T, Arai H, Yanai K, Kudo Y, Use of benzimidazole derivative BF-188 in fluorescence multispectral imaging for selective visualization of Tau protein fibrils in the Alzheimer’s disease brain, Mol Imaging Biol 16: 19-27, 2014
29. Uruno A, Saito-Hakoda A, Yokoyama A, Kogure N, Matsuda K, Parvin R, Shimizu K, Sato I, Kudo M, Yoshikawa T, Kagechika H, Iwasaki Y, Ito S, Sugawara A. Retinoic acid receptor-α up-regulates proopiomelanocortin gene expression in AtT20 corticotroph cells. Endocr J 61: 1105-1114, 2014
30. Yoshikawa T*, Naganuma F, Iida T, Nakamura T, Harada R, Mohsen A, Kasajima A, Sasano H, Yanai K, Molecular mechanism of histamine clearance by primary human astrocytes, Glia 61: 905-916, 2013 (*: corresponding author)
31. Okamura N, Furumoto S, Harada R, Tago T, Yoshikawa T, Fodero-Tavoletti M, Mulligan RS, Villemange VL, Akatsu, H, Yamamoto T, Arai H, Iwata R, Yanai K, Kudo Y, Novel 18F-labeled arylqunoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease, J Nucl Med 54: 1420-1427, 2013
32. Harada R, Okamura N, Furumoto S, Tago T, Maruyama M, Higuchi M, Yoshikawa T, Arai H, Iwata R, Kudo Y, Yanai K, Comparison of the binding characteristics of [18F]THK-523 and other amyloid imaging tracers to Alzheimer’s disease pathology, Eur J Nucl Med Mol Imaging 40: 125-132, 2013
33. Shibuya K, Funaki Y, Hiraoka K, Yoshikawa T, Naganuma F, Miyake M, Watanuki S, Sato H, Tashiro M, Yanai K, [(11)C]doxepin binding to histamine H1 receptor s in living human brain: reproducibility during attentive waking and circadian rhythm, Front Syst Neurosci, 6 :45, 2012
34. Ikeda T, Takasawa S, Noguchi N, Nata K, Yamauchi A, Takahashi I, Yoshikawa T, Sugawara A, Yonekura H, Okamoto H, Identification of a major enzyme for the synthesis and hydrolysis of cylic ADP-ribose in amphibian cells and evolutional conservation of the enzyme from human to invertebrate, Mol Cell Biochem, 366: 69-80 2012
35. Harada R, Furumoto S, Yoshikawa T, Ishikawa Y, Shibuya K, Okamura N, Iwata R, Yanai K, Synthesis of [11C]interleukin 8 using a cell-free translation system and L-[11C]methionine, Nucl Med Biol, 39: 155-160, 2011
36. Uruno A, Noguchi N, Matsuda K, Nata K, Yoshikawa T, Chikamatsu Y, Kagechika H, Harigae H, Ito S, Okamoto H, Sugawara A, All-transretinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expresion in human leukemia HL-60 cells: possible involvement of protein kinase C-delta, J Leukoc Biol, 90: 235-247, 2011
37. Yanai K, Zhang D, Tahiro M, Yoshikawa T, Naganuma F, Harada R, Nakamura T, Shibuya K, Okamura N, Positron emission tomography evaluation of sedative properties of antihistamines, Expet Opin Drug Saf, 10: 613-622, 2011
38. Uruno A, Matsuda K, Noguchi N, Yoshikawa T, Kudo M, Satoh F, Rainey, W, Hui XG, Akahira J, Nakamura Y, Sasano H, Okamoto H, Ito S, Sugawara A, Peroxisome proliferator-activated receptor-γ suppresses CYP11B2 expression and aldosterone production, J Mol Endocrinol, 19: 37-49, 2010
39. Okamura N, Mori M, Furumoto S, Yoshikawa T, Harada T, Ito S, Fujikawa Y, Arai H, Yanai K, Kudo Y, In vivo detection of amyloid plaques in the mouse brain using near-infrared fluorescence probe THK-265, J Alzheimers Dis 23: 37-48, 2010
40. Xu A, Sakurai E, Kuramasu A, Zhang J, Li J, Okamura N, Zhang D, Yoshikawa T, Watanabe T, Yanai K, Roles of hypothalamic subgroup histamine and orexin neurons on behavioral responses to sleep deprivation induced by the treadmill method in adlescent rats, J Pharmacol Sci 111: 444-453, 2010
41. Zhang D, Tashiro M, Shibuya K, Okamura N, Funaki Y, Yoshikawa T, Kato M, Yanai K, Next-day residual sedative effect after nighttime administration of an over-the-counter antihistamine sleep aid, diphenhydramine, measured by positron emission tomography, J Clin Psychophamacol 30: 694-701, 2010
42. Takasawa S, Kuroki M, Nata K, Noguchi N, Ikeda T, Yamauchi A, Ota H, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Takahashi I, Yoshikawa T, Shimosegawa T, Okamoto H, A novel ryanodine receptor expressed in pancreatic islets by alternative splicing from type 2 ryanodine receptor gene, Biochem Biophys Res Commun 397: 140-145, 2010
43. Zhou L, Zhang R, Wang L, Shen S, Okamoto H, Sugawara A, Xia L, Noguchi N, Yoshikawa T, Uruno A, Yao W, Yuan Y, Up-regulation of reg Ialpha accelerates tumor progression in pancreatic cancer with diabetes, Int J Cancer 127: 1795-1803, 2010
44. Okuda T, Zhang D, Shao H, Okamura N, Takino N, Iwamura T, Sakurai E, Yoshikawa T, Yanai K, Methamphetamine- and 3,4-Methylenedioxymethamphetamine-induced behavioral changes in histamine knockout mice. J Pharmacol Sci, 111: 167-174, 2009
45. Takahashi I, Noguchi N, Nata K, Yamada S, Kaneiwa T, Mizumoto S, Ikeda T, Sugihara K, Asano M, Yoshikawa T, Yamauchi A, Shervani NJ, Uruno A, Kato I, Unno M, Sugahara K, Takasawa S, Okamoto H, Sugawara A, Important role of heparan sulfate in postnatal islet growth and insulin secretion. Biochem Biophys Res Commun 383: 113-8, 2009
46. Yamauchi A, Takahashi I, Takasawa S, Nata K, Noguchi N, Ikeda T, Yoshikawa T, Shervani NJ, Suzuki I, Uruno A, Unno M, Okamoto H, Sugawara A, Thiazolidinediones inhibit REG Ialpha gene transcription in gastrointestinal cancer cells. Biochem Biophys Res Commun 379: 743-748, 2009
47. *Noguchi N, *Yoshikawa T, Ikeda T, Takahashi I, Shervani NJ, Uruno A, Yamauchi A, Nata K, Takasawa S, Okamoto H, Sugawara A, FKBP12.6 disruption impairs glucose-induced insulin secretion. Biochem Biophys Res Commun 371: 735-740, 2008 (*: co-first author)
48. Nakazawa T, Takasawa S, Noguchi N, Nata K, Tohgo A, Mori M, Nakagawara K, Akiyama T, Ikeda T, Yamauchi A, Takahashi I, Yoshikawa T, Okamoto H, Genomic organization, chromosomal localization, and promoter of human gene for FK506-binding protein 12.6, Gene 360: 55-64, 2005
